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A 58-year-old woman with multiple cranial neuropathies

Article Abstract:

A 58-year-old woman was admitted to a hospital after she developed difficulty swallowing, lost her speech and developed double vision. She was put on a ventilator and initially diagnosed with Guillain-Barre syndrome. However, this diagnosis did not completely explain her symptoms and she had further neurologic testing. The results indicated that she had botulism and stool samples tested positive for Clostridium (C.) botulinum. This bacterium produces a toxin that attacks the neuromuscular junction. Her family reported that she had tasted a jar of homemade spaghetti sauce and found it to be rancid. The sauce also tested positive for C. botulinum.

Author: Soto, Oscar, Hayes, Michael T., Ruoff, Kathryn L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Diagnosis, Sauces, Contamination, Botulism

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Case 33-2003: A 37-year-old man with a history of alcohol and drug abuse and sudden onset of leg weakness

Article Abstract:

A 37-year-old man who suddenly collapsed from leg weakness was diagnosed with a muscle disease caused by the drug colchicine, which he was taking for gout. His muscle strength gradually improved after he stopped taking the drug. However, he was admitted to a hospital for muscle weakness twice after he stopped taking the drug. This indicates that colchicine muscle damage may persist after the drug is discontinued.

Author: Hedley-Whyte, E. Tessa, Soto, Oscar
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
Causes of, Complications and side effects, Colchicine, Muscle weakness

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Case 1-2004: A 49-year-old woman with asymmetric painful neuropathy

Article Abstract:

A 49-year-old woman originally from India who was seen in a neurology clinic because of painful peripheral nerve disease and skin lesions was diagnosed with leprosy. Although leprosy was feared in ancient times, it is not particularly infectious. It is caused by a bacteria related to the bacteria that causes tuberculosis. The patient was treated with dapsone and rifampin.

Author: Hedley-Whyte, E. Tessa, Chad, David A.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Case studies, Leprosy

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