Brief report: Pneumocystis carinii osteomyelitis in a patient with common variable immunodeficiency

Article Abstract:

A 27-year-old black women with common variable immunodeficiency was diagnosed with Pneumocystis carinii pneumonia and extrapulmonary pneumocystis, or an infection caused by P. carinii that was outside the lungs. Common variable immunodeficiency is a condition of unknown cause that is characterized by abnormally low levels of immunoglobulins, or antibodies. The patient was admitted to the hospital with increasing pain in the left buttock, and had been experiencing fever, chills, and night sweats. She had given birth five months earlier, and had beta-thalassemia trait. The patient, her husband and her child were negative for infection with HIV-1. Analysis of a sputum sample, and a biopsy of tissue from her spine revealed the presence of P. carinii. The patient was treated with intravenous infusion of an antibiotic. Extrapulmonary pneumocystis is rare, and only 16 cases of extrapulmonary pneumocystis among patients without HIV infection have been reported in the medical literature. All of these patients had other conditions that lowered their immunity.

Health aspects, Causes of, Complications and side effects, Immunological deficiency syndromes, Immunologic deficiency syndromes, Osteomyelitis, Pneumocystis carinii

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A 59-year-old woman with an "apple core" lesion of the sigmoid colon, a pelvic mass, and a pulmonary nodule

Article Abstract:

A 59-year-old woman was diagnosed with small-cell cancer of the lung and squamous-cell cancer of the ovary and sigmoid colon. She had been admitted to a hospital with abdominal pain and intestinal obstruction. A CT scan showed a pelvic mass and a nodule on the upper lobe of the lung, which was found to be a small-cell cancer on biopsy. Laparoscopic surgery revealed an squamous cell ovarian tumor that had metastasized to the colon. The lung cancer was a primary cancer probably caused by longtime cigarette smoking.

Case studies, Squamous cell carcinoma, Lung cancer, Small cell, Small cell lung cancer

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