A controlled trial of bismuth subsalicylate in infants with acute watery diarrheal disease

Article Abstract:

Bismuth subsalicylate may be an effective and safe treatment for watery diarrhea in infants and toddlers. This drug has been available since the early 1900s, but its effectiveness and safety has only been tested recently. Among 252 male infants and toddlers who were hospitalized with watery diarrhea, 85 were treated with 100 milligrams (mg) of bismuth subsalicylate per kilogram (kg) of body weight per day, 83 were treated with 150 mg of bismuth subsalicylate per kg of body weight per day and 84 received a placebo, or an inactive substance, for up to five days. Eighty-nine percent of the children in the 100 mg group and 88% in the 150 mg group stopped having diarrhea within five days of being admitted to the hospital, compared with 74% of the children in the placebo group. The children treated with bismuth subsalicylate drank less oral rehydration fluid and were released from the hospital earlier than those who received a placebo.

Drug therapy, Bismuth subsalicylate

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Getting serious about cholera

Article Abstract:

The World Health Organization (WHO) has reported 46,758 cases of cholera, including 1893 deaths, as of June 19, 2006, in Angola. Various strategies that are used to prevent and manage cholera across the world are discussed.

Angola, Reports, Risk factors, Cholera, World Health Organization

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Racecadotril in the treatment of acute watery diarrhea in children

Article Abstract:

In a study of 135 boys aged 3 to 35 months suffering from diarrheal disease of viral or non viral nature, use of racecadotril (acetorphan) was found to be an effective and safe treatment.

Peru, Care and treatment, Statistical Data Included, Physiological aspects, Diseases, Rotavirus infections, Enkephalinase, Enkephalins

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