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A comparison of two antimicrobial-impregnated central venous catheters

Article Abstract:

Catheters that have antibiotics embedded in the plastic appear to reduce the risk of infection in people with central venous catheters. These catheters are used in critically ill patients to deliver food and medicines. Researchers compared infection rates in 817 patients at 12 hospitals, about half of whom received a catheter containing minocycline and rifampin and half of whom received a catheter containing chlorhexidine and silver sulfadiazine. Infection rates were much lower in patients who received the minocycline/rifampin catheters. The antibiotics were applied to the inside and outside of the catheter, whereas chlorhexidine/sulfadiazine was only applied to the outside.

Author: Mayhall, Glen, Darouiche, Rabih O., Harris, Richard L., Gabrielli, Andrea, Hachem, Ray, Raad, Issam I., Heard, Stephen O., Thornby, John I., Wenker, Olivier C., Berg, Johannes, Khardori, Nancy, Hanna, Hend
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Usage, Innovations, Infection, Antibiotics, Prevention, Composition, Intravenous catheterization, Catheters

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Prognosis and decisions in pneumonia

Article Abstract:

Development of a prediction rule for the risk of death of pneumonia patients may be helpful, but ultimately, the decision of whether to hospitalize a pneumonia patient should be the doctor's. A recent study of patients with community-acquired pneumonia identified 19 factors that could be used to predict the risk of death from pneumonia and the need for hospitalization. Patients under 50 without coexisting history of illness or physical dysfunction have the lowest risk of death, according to the prediction rule. The rule has not been tested in a large research study.

Author: Farr, Barry M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Care and treatment, Editorial, Pneumonia, Nosocomial infections, Cross infection

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