A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, patients with rheumatoid arthritis receiving methotrexate

Article Abstract:

Etanercept in addition to methotrexate may be more effective than methotrexate alone in treating rheumatoid arthritis. Etanercept is a drug that inhibits the action of tumor necrosis factor, which causes inflammation. Researchers randomly assigned 89 rheumatoid arthritis patients to take methotrexate alone or methotrexate and etanercept. After six months of treatment, 71% of the patients taking both drugs experienced a 20% improvement in function and 39% experienced a 50% improvement. The percentages of people taking methotrexate alone who achieved these results were 27% and 3%, respectively.

Rheumatoid arthritis, IMNX, Methotrexate

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Etanercept as monotherapy in patients with psoriasis

Article Abstract:

The drug Enbrel may be effective in treating severe psoriasis, according to a study of 652 patients. The drug was given as a subcutaneous injection once a week for up to six months. Between 25% and 59% of the patients had a 75% or greater improvement in symptoms, depending on the dose. Enbrel blocks the activity of tumor necrosis factor, which is believed to cause some of the symptoms of psoriasis.

Product information, Pharmaceutical industry

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Etanercept treatment for children and adolescents with plaque psoriasis

Article Abstract:

A study analyzes the efficacy and safety of etanercept in children and adolescents with moderate-to-severe plaque psoriasis. Findings reveal the capability of etanercept in significantly reducing disease severity in children and adolescents with moderate-to-severe plaque psoriasis.

Patient outcomes, Complications and side effects, Dosage and administration, Tumor necrosis factor, Tumour necrosis factor, Etanercept, Clinical report

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