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A universal influenza A vaccine based on the extracellular domain of the M2 protein

Article Abstract:

An influenza vaccine created from the M2 protein of influenza A virus fused to the hepatitis B virus core protein protected 90% to 100% of the mice that received it from a lethal virus challenge. The M2 protein is a minor part of the virus but is very stable and does not drift as other viral proteins do.

Author: Fiers, Walter, Neirynck, Sabine, Deroo, Tom, Saelens, Xavier, Vanlandschoot, Peter, Jou, Willy Min
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Evaluation, Influenza vaccines

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New multi-determinant strategy for a group A streptococcal vaccine designed for the Australian Aboriginal population

Article Abstract:

Researchers describe the creation of a vaccine against group A streptococci that includes seven serotypic peptides hanging from an alkane backbone. Group A streptococci cause rheumatic fever and rheumatic heart disease, most notably in poor populations such as Australian aborigines.

Author: Brandt, Evelyn R., Sriprakash, K.S., Hobb, Rhonda I., Hayman, Wendy A., Zeng, Weiguang, Batzloff, Michael R., Jackson, David C., Good, Michael F.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Research, Streptococcal infections, Prevention, Bacterial vaccines, Rheumatic heart disease, Rheumatic fever

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Varicella-zoster vaccine: the bad news may be good

Article Abstract:

The chickenpox vaccine appears to be capable of reactivating and causing a mild form of chicken pox. However, this could be beneficial because it might stimulate the immune system to fight the native virus.

Author: Mills, John
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Physiological aspects, Chickenpox vaccine, Chickenpox vaccines

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