Adverse cerebral outcomes after coronary bypass surgery

Article Abstract:

A number of cerebral complications may occur after coronary bypass surgery. Researchers found such adverse outcomes in 6.1% of 2,108 bypass patients, including death, stroke, seizures, stupor, and intellectual deterioration. Complications caused more deaths while in the hospital, longer hospital stays, and more referrals to care facilities. Atherosclerotic conditions common in advanced age were leading factors for surgical complications, followed by hypertension, pulmonary disease, and alcohol abuse. Future interventional strategies should reduce risk and conserve resources.

Health aspects, Stroke (Disease), Stroke, Coronary artery bypass, Cerebral embolism and thrombosis, Cerebral embolism, Cerebral thrombosis

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Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery

Article Abstract:

Giving people with coronary artery disease a beta-blocker such as atenolol during non-cardiac surgery may reduce their risk of experiencing myocardial ischemia. Myocardial ischemia occurs when the blood supply to the heart is reduced, which sometimes occurs during non-cardiac surgery. Researchers gave 99 patients atenolol before and after non-cardiac surgery and 101 patients a placebo. All 200 patients had a history of or risk factors for coronary artery disease. Atenolol increased 2-year event-free survival rates by 15%. The drug was well tolerated with few side effects.

Evaluation, Prevention, Surgery, Postoperative complications, Ischemia, Cardiac patients, Atenolol

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The risk associated with aprotinin in cardiac surgery

Article Abstract:

A study on use of aprotinin was associated with a dose-dependent doubling to tripling in the risk of renal failure requiring dialysis among patients undergoing primary and complex coronary-artery surgery. The findings indicate that reconsideration of the safety of aprotinin among patients undergoing cardiac surgery is warranted and indicate replacement of aprotinin with either aminocaproic acid or tranexamic acid.

United States, Methods, Usage, Risk factors, Hemodialysis, Kidney failure, Tranexamic acid

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