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Amniotic fluid concentrations of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 during pregnancy and labor

Article Abstract:

Matrix metalloproteinase 9 is present in the amniotic fluid of pregnant women who have uterine infections as well as in those who are in labor or whose membranes have ruptured. This enzyme is involved in breaking down tissues and appears to be involved in abnormal as well as normal physiologic processes.

Author: Saade, George R., Locksmith, Gregory J., Clark, Penny, Duff, Patrick, Schultz, Gregory S.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
Physiological aspects, Labor (Obstetrics)

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Amniotic fluid matrix metalloproteinase-8 indicates intra-amniotic infection

Article Abstract:

The presence of an enzyme called matrix metalloproteinase-8 in amniotic fluid may be a marker of an infection inside the uterus. The enzyme can be detected using an ELISA test.

Author: Strauss, Jerome F., III, Macones, George A., Locksmith, Gregory J., Clark, Penny, Sammel, Mary D., Angus, Stanley R., Segel, Sally Y., Hsu, Chaur-Dong, Parry, Samuel
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
Health aspects, Analysis, Enzyme-linked immunosorbent assay, Amniotic fluid

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Maternal and neonatal infection rates with three different protocols for prevention of group B streptococcal disease

Article Abstract:

Universal screening for group B streptococcal infection in pregnant women may reduce the incidence of serious complications in the mother but may not reduce the rate of transmission to the fetus. Researchers compared the outcome of group B streptococcal infection under three different screening strategies. The universal strategy screened all pregnant women whereas the other two only screened women perceived to be at high risk. The rate of serious streptococcal infection was slightly lower in the universal screening group. However, half the neonatal infections in the universal screening group occurred in women who were not treated.

Author: Locksmith, Gregory J., Clark, Penny, Duff, Patrick
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
Evaluation, Streptococcal infections, Medical examination, Pregnant women, Disease transmission, Medical screening, Health screening

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Subjects list: Infection, Metalloenzymes, Uterus
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