Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection

Article Abstract:

Levels of the enzyme matrix metalloproteinase-9 increase in amniotic fluid during the rupture of fetal membranes and also during uterine infection. This enzyme breaks down fetal membranes.

Metalloenzymes

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Lactoferrin in intrauterine infection, human parturition, and rupture of fetal membranes

Article Abstract:

Levels of lactoferrin in amniotic fluid increase when the uterus becomes infected, according to a study of 268 pregnant women. Lactoferrin is a protein in amniotic fluid that transports iron, and it is known to have antibacterial properties.

Lactoferrins

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Participation of hte novel cytokine interleukin 18 in the host response to intra-amniotic infection

Article Abstract:

The production of interleukin-18 is increased in pregnant women who have an intra-uterine infection, according to a study of 285 pregnant women. Interleukin-18 is a pro-inflammatory substance produced by the immune system that is believed to protect humans from infection.

Interleukins, Chorioamnionitis

Similar abstracts:

• Abstracts: Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection
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• Abstracts: Role of amnioinfusion in the management of premature rupture of the membranes at less than 26 weeks' gestation

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