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Antiretroviral regimen complexity, self-reported adherence, and HIV patients' understanding of their regimens: Survey of women in the HER study

Article Abstract:

The authors discuss a study to determine factors involved in HIV patients maintaining their medication regimen. They surveyed participants and based their data on the patients' reports of their own compliance with the medication schedule. They found that the more complex the regimen becomes, the worse the self-reporting and the ability to adhere to the antiretroviral therapy becomes, indicating that simplification of drug therapy is more desirable.

Author: Schuman, Paula, Stone, Valerie E, Hogan, Joseph W, Rompalo, Anne M, Howard, Andrea A, Korkontzelou, Christina, Smith, Dawn K
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
Statistics, Patient compliance

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Priorities for antiretroviral therapy research in sub-Saharan Africa

Article Abstract:

Consensus conference was held in 2002 to discuss priorities for antiretroviral therapy (ART) research in Zambia, one of the world's most heavily HIV-afflicted nations, having increasing access to highly active antiretroviral therapy (HAART). The participants felt that the research priorities were to assess how therapeutic resources could be applied for the greatest overall benefit and to minimize the impact of nonadherence and viral resistance.

Author: Vermund, Sten H., Schuman, Paula, Sinkala, Moses, Zulu, Isaac, Kasonde, Dorothy, Musonda, Rosemary, Mwaba, Peter, Chomba, Elwyn, Chisembele, Mauren, Mwinga, Kasonde
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2004
Zambia, Highly active antiretroviral therapy

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Persistent abnormalities in peripheral blood dendritic cells and monocytes from HIV- 1- positive patients after 1 year of antiretroviral therapy

Article Abstract:

The effect of antiretroviral therapy (ART) on numerical distribution, expression of chemokine receptors, and ex vivo production of inflammatory cytokines by peripheral blood (PB) monocytes and dendritic cells (DC's) in a cohort of chronically infected HIV- 1-positive patients is analyzed. The results show an incomplete T- cell immune reconstitution in chronically infected patients who had undetectable plasma viremia while taking ART for 1 year.

Author: Almeida, Maria, Cordero, Miguel, Almeida, Julia, Orfao, Alberto
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
Patient outcomes, Antiviral agents, Antiretroviral agents, Dendritic cells

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Subjects list: United States, Drug therapy, HIV patients, Research
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