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Are women with recurrent spontaneous preterm births different from those without such history?

Article Abstract:

A study was undertaken to determine whether women with recurrent spontaneous preterm births (rSPBs) having different clinical characteristics or systemic markers than those with isolated preterm (iSPBs) or recurrent term births (rTBs), when assessed remote from delivery. Women with rSPBs are leaner, contract more, have shorter cervixes, and have more advanced Bishop scores than women with iSPBs or rTBs.

Author: Goldenberg, Robert L., Miodovnik, Menachem, Mercer, Brian M., Moawad, Atef H., Meis, Paul J., Iams, Jay D., Caritis, Steve N., Thurnau, Gary R., Sorokin, Yoram, Spong, Catherine Y., Varner, Michael W., Goepfert, Alice R., Macpherson, Cora A., Van Dorsten, Peter J., Mouzon, Sylvie Haugel- De
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
Women, Women's health, Premature birth, Labor, Complicated, Labor complications, Labour complications

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Perinatal outcomes in women with preterm rupture of membranes between 24 and 32 weeks of gestation and a history of vaginal bleeding

Article Abstract:

Perinatal outcomes among women with conservatively treated preterm premature rupture of membranes at 24 to 32 weeks of gestation in the presence or absence of vaginal bleeding are compared. Vaginal bleeding before preterm premature rupture of membranes is associated with increased rates of neonatal respiratory distress syndrome and abruptio placentae, but not with reduced latency to delivery.

Author: Thom, Elizabeth A., Thurnau, Gary, Mercer, Brian M., Moawad, Atef H., Meis, Paul J., Iams, Jay D., Hnat, Michael D., Goldenberg. Robert, Van Dorsten, J. Peter
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2005
United States, Health aspects, Causes of, Birth defects, Premature rupture of membranes, Premature rupture of the membrane, Vagina, Vaginal bleeding

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Reciprocal expression of peroxisome proliferator-activated receptor-gamma and cyclooxygenase-2 in human term parturition

Article Abstract:

The association of the reciprocal repression of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) with an up regulation of cyclooxygenase-2 (COX-2) in human parturition is described. Once the active labor commences the PPAR-gamma levels are reduced in the fetal membranes and are coincidental with a relative increase in COX-2 expression.

Author: Iams, Jay D., Kniss, Douglas A., Dunn-Albanese, Lisa R., Ackerman, William E., Yubing Xie
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
Complications and side effects, Pregnancy, Placenta, Peroxisomes

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