Arteriovenous malformations of the brain in adults

Article Abstract:

About 300,000 Americans may have an arteriovenous malformation in the brain. An arteriovenous malformation is a mass of abnormal arteries and veins that form a clump. Data from autopsies reveals that only a minority will cause any symptoms during life. Rupture can cause a stroke but only 2% of strokes are caused by a ruptured arteriovenous malformation. Many such stroke patients may have a good prognosis depending on where the malformation is located in the brain. Surgery is the best treatment but radiotherapy can also damage the malformation, leading to its destruction.

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The risk of hemorrhage after radiosurgery for cerebral arteriovenous malformations

Article Abstract:

Patients with cerebral arteriovenous malformations who are treated with radiosurgery are studied and the rates of hemorrhage before radiosurgery, during latency period and after angiographic obliteration are assessed. It is found that radiosurgery significantly decreases the risk of hemorrhage in patients with cerebral arteriovenous malformations, even before there is angiographic evidence of obliteration, and that the risk of hemorrhage is further reduced after obliteration.

United States, Methods, Hemorrhage, Radiosurgery

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Major congenital malformations after first-trimester exposure to ACE inhibitors

Article Abstract:

A study investigates the association between exposure to angiotensin-converting-enzyme (ACE) inhibitors during the first trimester of pregnancy only and the risk of congenital malformations. Results with only first-trimester exposure to ACE inhibitors showed an increased risk of major congenital malformations as compared with infants who had no exposure to antihypertensive medications, indicating that exposure to ACE inhibitors cannot be considered safe and should be avoided.

Science & research, Research, Usage, ACE inhibitors, Angiotensin converting enzyme inhibitors, Genetic disorders, Angiotensin converting enzyme, Disease/Disorder overview

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