Assessing the duration of mandibular soft tissue anesthesia

Article Abstract:

Local anesthetic solutions of 3% mepivacaine or 4% prilocaine do not appear to reduce the duration of lip and tongue numbness compared to 2% lidocaine with epinephrine. Some dentists use anesthesia without a vasoconstrictor such as epinephrine in children because they believe it shortens the duration of lip and tongue numbness. Researchers injected a local anesthetic into the mouths of 60 adults. Twenty received 2% lidocaine with epinephrine, twenty-one received 3% mepivacaine, and 19 received 4% prilocaine. Participants rated the intensity of lip and tongue numbness at 15 minute intervals for five hours. The average onset, peak effects, and duration of numbness was similar among all treatment groups throughout the study period. Participants reported lip and tongue numbness within five minutes after the injection, peak effects between 30 and 45 minutes, and diminishing numbness between 90 and 120 minutes.

Lidocaine

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Interactions associated with analgesics

Article Abstract:

Nonsteroidal antiinflammatory drugs (NSAIDs) and other analgesics commonly used in dentistry can adversely interact with other prescription medications. NSAIDs inhibit prostaglandin synthesis, and may interact with angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, and other antihypertensive drugs to reduce their effectiveness and elevate blood pressure. NSAIDs may increase the blood levels lithium, digoxin, methotrexate, and anticonvulsants, and may increase the risk of bleeding in patients on anticoagulant medications. The use of NSAIDS and opioids with alcohol, or in patients with alcoholic liver disease, is not recommended.

United States, Complications and side effects, Physiological aspects, Opioids, Nonsteroidal anti-inflammatory drugs, Nonsteroidal anti-inflammatory agents, Drug interactions

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Injection pain: comparison of three mandibular block techniques and modulation by nitrous oxide:oxygen

Article Abstract:

The three most common injections for numbing teeth are all equally painful, according to a study of 60 dental patients. The injections are the standard inferior alveolar nerve block, the Gow-Gates nerve block, and the Vazirani-Akinosi nerve block. Nitrous oxide:oxygen can reduce the pain of the injection, but only on the first injection.

Causes of, Pain, Injections

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