Budesonide turbuhaler for asthma

Article Abstract:

The first dry-powder oral inhaler for treatment of asthma is being marketed by Astra under the name Pulmicort Turbuhaler. The active ingredient, budesonide, a corticosteroid, has previously been available as a nasal spray for allergic rhinitis. Other corticosteroids for asthma come in metered dose inhalers which use a propellant. The Turbuhaler is powered by the inhaled breath and seems to deliver twice as much of the drug to the lungs as a propellant-powered metered dose device.

Innovations, Drug delivery systems, Dosage and administration, Antiasthmatic agents

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Zileuton for asthma

Article Abstract:

The FDA has approved zileuton for the treatment of asthma. Sold under the trade name Zyflo, the drug belongs to a class of drugs called leukotriene inhibitors. Leukotrienes are an inflammatory chemical produced from arachidonic acid. Zileuton inhibits this process. It has been shown to be effective in preventing exacerbations of asthma. Unfortunately, the drug can damage the liver, so children who take it must be monitored for liver damage.

Evaluation, Product/Service Evaluation, Zyflo (Medication)

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Omalizumab (Xolair): an ani-IgE antibody for asthma

Article Abstract:

Omalizumab (Xolair) is for use by paients at least 12 years old with moderate to severe persistent asthma, which is inadequately controlled by corticosteroid inhalers. The humanized monoclonal anti-IgE antibody drug given subcutaneously reduces the number of asthma exacerbations. It is FDA approved and not cost-effective for all users.

United States, Surgical Appliance and Supplies Manufacturing, Surgical and medical instruments, Inhalators, Usage, Corticosteroids, Adrenocortical hormones, Drug use, Inhalers, Anti-antibodies, Corticosteroid drugs

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