Immune function and neuropsychological performance in HIV-1-infected homosexual men

Article Abstract:

People with HIV infection may not experience a decline in intellectual capability until their immune system starts to fail. Fifty-five HIV-positive men and 37 HIV-negative men had a physical exam, gave blood samples for analysis and took various psychological tests. They were grouped according to their blood levels of CD4 lymphocytes and beta2-microglobulin, which are measures of immune function. In general, the HIV-positive group scored slightly higher on measures of memory and attention than the HIV-negative control group. However, HIV-positive men who had impaired immune systems scored lower on the tests than HIV-positive men with intact immune systems. Men with more advanced HIV infection scored no worse on the tests than those with mild infection.

Psychological aspects, HIV patients, Gay men

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A prospective study of dietary intake and acquired immune deficiency syndrome in HIV-seropositive homosexual men

Article Abstract:

A healthy diet may delay the development of AIDS in individuals who are HIV-positive. Different types of nutrients may decrease impairment of the immune system and prevent protein energy malnutrition. Among 296 HIV-positive homosexual men between 25 and 50 years old whose dietary intake was examined, 107 (36%) developed AIDS over a six-year follow-up period. Increased consumption of 11 micronutrients was associated with a lower risk of developing AIDS. A significant association was found for increased consumption of iron, vitamin E and riboflavin. Individuals with higher consumption of all 11 micronutrients initially had higher blood levels of CD4 T-cells. Daily consumption of multivitamins was also associated with a lower risk of developing AIDS.

Health aspects, Development and progression, HIV infection, HIV infections, Food and nutrition, AIDS patients, Diet

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Invited commentary: needle exchange - no help for hepatitis?

Article Abstract:

The authors comment on the real benefits of needle exchange programs in view of recent research which contradicts earlier claims. Studies have shown either a reduction of infectious disease in drug users or no apparent benefit while in exchange programs. More rigorous research is urgently needed.

Evaluation, Risk factors, Needle exchange programs, Hepatitis

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