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Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland

Article Abstract:

Environmental contaminants that mimic the effect of estrogen contribute to disruption of the reproductive systems of animals in the wild, and to the high incidence of hormone-related cancers and diseases in western population, are mentioned. Present studies show that Cadmium also has potent estrogen like activity in vivo.

Author: Johnson, Michael D., Clarke, Robert, Trock, Bruce, Kenney, Nicholas, Stoica, Adriana, Hilakivi-Clarke, Leena, Singh, Baljit, Chepko, Gloria, Sholler, Peter F., Lirio, Apolonio A., Foss, Colby, Reiter, Ronald, Paik, Soonmyoung, Paik, Martin, Mary Beth
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Estrogen & Progestogen Preps, Pollutants, Estrogen, Estrogens

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Cadmium's disguise dupes the estrogen receptor

Article Abstract:

Studies show that Cadmium is a toxic environmental pollutant that has worrisome estrogenic effect in cell culture. Results highlights that cadmium can act as an estrogen mimic in the whole animal, inducing conditions ranging from uterine hyperplasia to early onset of puberty.

Author: Safe, Stephen
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Cell culture, Hyperplasia

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Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome

Article Abstract:

The different results of stress with relevance to body weight, the role of neuropeptide Y on adipose tissue are examined.

Author: Johnson, Michael D., Baker, Stephen B., Li, Lijun, Tilan, Jason U., Kitlinska, Joanna B., Kuo, Lydia E., Lee, Edward W., Burnett, Mary Susan, Ficke, Stanley T., Zukowska, Zofia, Herzog, Herbert, Kvetnansky, Richard
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
United States, Health aspects, Causes of, Obesity, Adipose tissues, Adipose tissue, Neuropeptide Y, Metabolic diseases

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Subjects list: Research, Influence, Environmental aspects, Cadmium
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