Can successful vaccines teach us how to induce efficient protective immune responses?

Article Abstract:

Successful vaccines have often emerged out of empirical observations and have only rarely been the result of a rational use of the continuously increasing immunological knowledge available to scientists. However, a posteriori deciphering of the biological bases for the efficacy of successful vaccines should be an essential component of research efforts directed at the development of new vaccines for the most challenging infectious diseases.

Vaccines

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Targeting the innate immune response with improved vaccine adjuvants

Article Abstract:

Adjuvants and delivery systems have become important for the development of new subunit vaccines consisting of isolated antigens because their invasiveness provides efficient delivery to antigen presenting cells and helps in stimulating the innate immune system. Details of the discovery and development of immunostimulatory compounds and vaccine formulations that target innate immune response are discussed.

Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Drug Delivery Systems, Usage, Drugs, Adjuvants, Pharmaceutic, Adjuvant drugs

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