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Carrier Rates in the Midwestern United States for GJB2 Mutations Causing Inherited Deafness

Article Abstract:

All people with congenital deafness should be tested for the 35delG mutation of the GJB2 gene. Mutations in this gene are the most common cause of congenital deafness. In a study of 52 people with profound congenital hearing loss, 42% had a mutation in the GJB2 gene. The 35delG mutation accounted for 29 of the 41 mutations. Of 560 people with normal hearing, 3% had a GJB2 mutation and 2.5% were carriers of the 35delG mutation. Adults who have a GJB2 mutation should receive genetic counseling.

Author: Woodworth, George G., Sheffield, Val C., Smith, Richard J.H., Green, Glenn E., Scott, Daryl A., McDonald, Joshua M.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Statistics, Gene mutations, Gene mutation, Genetic aspects, Deafness

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Trends in the association of poverty with overweight among US adolescents, 1971-2004

Article Abstract:

A study examines trends in adolescent overweight in the US from 1971 to 2004 by family poverty status as well as trends in potentially relevant eating and physical activity behaviors. Trends of increasing overweight show a greater impact in families living below the poverty line as compared to those not living below the poverty line among the 15 to17 age group but not among adolescents aged 12 to 14 years.

Author: Kumanyika, Shiriki K., Link, Bruce G., Miech, Richard A., Stettler, Nicolas, Phelan, Jo C., Chang, Virginia W.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
United States, Science & research, Health aspects, Research, Causes of, Obesity, Poverty

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