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Case 18-2003: A 15-year-old girl with pain in the left leg and back, pruritus, and thoracic lymphadenopathy

Article Abstract:

A 15-year-old girl with itching, pain in her left leg and back, and enlarged lymph nodes in her chest was diagnosed with advanced Hodgkin's lymphoma. This is a cancer of B cells, which are part of the immune system. This patient had the nodular lymphocyte-predominant form of Hodgkin's lymphoma. She was successfully treated with chemotherapy.

Author: Lehmann, Leslie E., Anupindi, Sudha, Harris, Nancy Lee
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
Hodgkin's disease

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Case 28-2004: newborn twins with thrombocytopenia, coagulation defects, and hepatosplenomegaly

Article Abstract:

A case study is presented of two identical male infants who showed symptoms of fever, splenomegaly, hepatomegaly, thrombocytopenia, neutropenia, hypofibrinogenemia, and hyperbilirubinemia. The pathological diagnosis indicated familial hemophagocytic lymphohistiocytosis, caused by a mutation in the perforin gene.

Author: Harris, Nancy Lee, Lipton, Jeffrey M., Westra, Sjirk, Haverty, Carrie E., Roberts, Drucilla
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Risk factors, Gene mutations, Gene mutation, Pediatric diseases, Children, Genetic disorders

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Case 29-2005: A 68-year-old man with periorbital swelling, rash, and weakness

Article Abstract:

A review on dermatomyositis, caused due to a malignant tumor in the abdomen is presented with reference to a case study of a 68-year-old man admitted to hospital for rash and muscular debilitation. Two doctors working on the case offer the pathological discussion on dermatomyositis along with their diagnosis.

Author: Polisson, Richard P., Harris, Nancy Lee, Duncan, Lyn M., Crocker, Jonathan T.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
New England States, Diagnosis, New England, Dermatomyositis

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Subjects list: Case studies
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