Changes in hepatitis C virus (HCV) viral load and interferon-alpha levels in HIV/HCV-coinfected patients treated with highly active antiretroviral therapy

Article Abstract:

The impact of highly active antiretroviral therapy (HAART) on hepatitis C virus (HCV) RNA titer and transaminase levels in HIV/HCV-coinfected persons is evaluated for liver transaminase levels, HCV RNA titers and interferon-alpha levels. In conclusion, few patients had drug-induced heptatotoxicity associated with initiation of HAART, but HAART use was not associated with a significant increase in liver transaminase levels for the group as whole.

Health aspects, Interferon alpha, Highly active antiretroviral therapy, Hepatitis C virus

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Prognostic factors for survival differ according to CD4+ cell count among HIV-infected injection drug users: Pre-HAART and HAART eras

Article Abstract:

A study is done to identify prognostic indicators of survival at different CD$+ cell levels, independent of highly active antiretroviral therapy (HAART), among injection drug users (IDUs). The results showed that survival among HIV-infected IDUs improved since the introduction of HAART, even though utilization of HAART was incomplete.

Risk factors, Prognosis, HIV infection, HIV infections, Intravenous drug abuse

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