Changes in total lymphocyte count as a surrogate for changes in CD4 count following initiation of HAART: implications for monitoring in resource-limited settings

Article Abstract:

A retrospective cohort study was conducted to examine the capability and clinical utility of total lymphocyte count (TLC) changes as a surrogate marker for CD4 count change while monitoring patients with HAART that has important implications for resource-limited settings. Results indicate that the variability could be reduced and the predictive accuracy could be improved by taking multiple readings of TLC at frequent intervals.

United States, Science & research, Research, CD4 lymphocytes, Highly active antiretroviral therapy, Blood cell count, White blood cell count

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Plateau in body habitus changes and serum lipid abnormalities in HIV-positive women on highly active antiretroviral therapy: a 3.5-year study

Article Abstract:

Most changes in body composition in female HIV patients taking highly active antiretroviral therapy (HAART) occur within the first year and usually stabilize after 2.5 years. However, blood levels of fats and cholesterol become elevated, which is a risk factor for cardiovascular disease.

Causes of, Body composition, Lipid metabolism disorders, Lipidosis

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Changes in body habitus and serum lipid abnormalities in HIV-positive women on highly active antiretroviral therapy (HAART)

Article Abstract:

Highly active antiretroviral therapy (HAART) can have adverse effects on blood lipids that can increase the patient's risk of heart disease. This was seen in a study of 21 women who developed abnormal fat deposits and elevated cholesterol levels.

Complications and side effects, Antiviral agents, Fat metabolism

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