Chromosomal abnormalities and birth defects among couples with colchicine treated familial Mediterranean fever

Article Abstract:

A study is conducted to determine whether colchicine prescribed for familial Mediterranean fever is teratogenic. The results suggest that the existing policy of routine amniocentesis in pregnancies of couples taking colchicine should not be changed until sufficient data accumulates to establish whether the higher number of chromosomal anomalies in this group is significant.

Care and treatment, Chromosome abnormalities, Familial Mediterranean fever, Periodic disease, Colchicine

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Assessing the risk of berth defects associated with antiretroviral exposure during pregnancy

Article Abstract:

The purpose of the study was to examine teratogenic risk of antiretroviral (AVR) drugs. Antiretroviral Pregnancy Registry data demonstrate no increase in prevalence of birth defects overall or among women exposed to lamivudine, nelfinavir, nevirapine, stavudine, and zidovudine.

Antiviral agents, Teratogenic agents, Antiretroviral agents

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Meperidine for dystocia during the first state of labor: A randomized controlled trial

Article Abstract:

Decrease in length of labor in patients with a diagnosis of dystocia during first stage of labor was evaluated with the administration of meperidine. It was concluded that as it resulted in harmful effects on neonatal outcomes, meperidine should not administered.

Drug therapy, Dosage and administration, Dystocia, Meperidine

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