Comparison of normal saline and heparin solutions for maintenance of arterial catheter patency

Article Abstract:

Catheters can be placed in arteries to continuously monitor pressure and to be able to sample blood or to inject fluids without numerous punctures. The catheter is constantly filled and flushed with fluid, usually a 0.9 percent sodium chloride (saline) solution that may also contain heparin, a drug that prevents blood coagulation. This solution is supposed to keep the catheter clear of obstructions and functioning. This study examined whether the heparin was useful in maintaining catheter patency (openness) by comparing solutions with and without heparin. Also studied were any side effects the various solutions might elicit. Thirty patients having arterial catheters placed in their radial arteries were randomly assigned either to group I, which used a 0.9 percent sodium chloride (NSS) flushing solution, or to group II, which used a similar solution with heparin added to it. The functional life spans of the arterial catheters were measured. Results showed catheter failure occurred in five patients in group I and in one patient from group II. Catheter patency after 40 and 96 hours was significantly less in the NSS group than in the group using heparin. Catheter obstructions were significantly greater in the NSS group than in the heparin group. No side effects from either solution were seen. These results show that heparin added to saline solutions increases the length of catheter patency and decreases the incidence of occlusions. Therefore heparin-containing solution is recommended over plain solutions. (Consumer Summary produced by Reliance Medical Information, Inc.)

Equipment and supplies, Maintenance and repair, Heparin, Arterial catheterization, Catheters, Saline irrigation

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Selecting an Aspirin Dosage for the Secondary Prevention of Myocardial Infarction

Article Abstract:

Issues related to the usage of aspirin to prevent coronary artery disease are examined. Topics include the history of aspirin use, the pathophysiology of platelet inhibition, adverse effects, and review of aspirin investigations.

United States, Health aspects, Prevention, Coronary heart disease, Aspirin

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