Complement and regulatory genes and hemolytic uremic syndromes

Article Abstract:

The article discusses mutations in the complement and regulatory genes that causes hemolytic uremic syndromes, a triad of hemolytic anemia with prominent endothelial cell injury. The plasma infusion/ exchange and the complement inhibitor therapy are found to be the most effective therapies for the treatment of the disorder.

Injuries, Genetic aspects, Genetic regulation, Endothelium, Mutation (Biology), Mutation, Hemolytic-uremic syndrome

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Mesenchymal stem cells in acute kidney injury

Article Abstract:

The article explains significance of the mesenchymal stem cells (MSCs) in the various repair and cell-based therapies that are employed for the treatment of acute kidney injury (AKI). MSCs are derived from the bone-marrow and facilitate the functional repair of the injured nephrons.

Health aspects, Care and treatment, Gene expression, Stem cells, Kidney diseases

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