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Comprehensive volumetric optical microscopy in vivo

Article Abstract:

A fiber-optic imaging technique termed optical frequency-domain imaging (OFDI) that allows acquiring high-resolution cross-sectional images through flexible narrow-diameter catheters is used to show microscopy of esophageal mucosa and of coronary arteries in vivo. The results suggest that this technology might be a useful clinical tool for comprehensive diagnostic imaging for epithelial disease and for evaluating coronary pathology and iatrogenic effects.

Author: Nishioka, Norman S., Seok H Yun, Tearney, Guillermo J., Vakoc, Benjamin J., Shishkov, Milen, Wang Y Oh, Desjardins, Adrien E., Suter, Melissa J., Raymond C. Chan, Evans, John A., Ik-Kyung Jang, de Boer, Johannes F., Bouma, Brett E.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
Optical Instrument and Lens Manufacturing, Optical instruments and lenses, Optical Fiber Test Equip, Usage, Medical examination, Esophagus, Fiber optic test equipment, Fibre optic test equipment

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Volumetric computed tomography (VCY): A new technology for noninvasive, high-resolution monitoring of tumor angiogenesis

Article Abstract:

Volumetric computed tomography (VCT) is a technology in which area detectors are used for imaging large volumes of a subject with isotropic imaging resolution and this technique was used to demonstrate microangiography of xeno-transplanted skin sqamous cell carcinomas in nude mice. VCT substantially improves imaging of vascularization in tumors and offers a promising tool for preclinical studies of tumor angiogenesis and antiangiogenic therapies.

Author: Kiessling, Fabian; Greschus, Sussane, Lichy, Matthias P.; Bock, Michael, Fink, Christian; Vosseler, Silvia, Moll, Jens; Fusening, Norbert E., Traupe, Horst; Semmler, Wolfhard
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Diagnosis, Technology application, Cancer, Angiography, Tomography, Carcinoma

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Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography

Article Abstract:

This article shows how macrophages, which are vital elements of the immune system, in a rabbit can be seen with a clinical x-ray computed tomography (CT) scanner after being injected with a compound of iodinated nanoparticles. This study is done so that on early detection of atherosclerotic plaques in coronary arteries, the patient may have some chance of survival and recovery.

Author: Gordon, Ronald, Fuster, Valentin, Hyafil, Fabien, Cornily, Jean-Chritophe, Feig, Jonathan E, Vucic, Esad, Amirbekian, Vardan, Fisher, Edward A, Feldman, Laurent J, Fayad, Zahi A
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Science & research, Research, Analysis, Physiological aspects, CT imaging, CAT scans, Immune system, Rabbits

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Subjects list: United States
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