Computer-based drug-utilization review - risk, benefit, or boondoggle?

Article Abstract:

There appears to be very little data to support using computer-based drug utilization review. Drug utilization review is a program that employs established criteria in evaluating drug use to prevent incorrect prescribing. Claims that drug utilization reviews reduce illness and hospitalization are based on faulty studies. Care should be exercised in imposing administrative restrictions on drug use. In one study, use of anti-inflammatory drugs was reduced substantially, but people with arthritis could be affected adversely. Information about drugs should come from an unbiased, credible source. The source of therapeutic recommendations should be revealed, especially if it is a pharmaceutical company that has a financial interest in the sale of the drug.

Drugs, Finance, Information management, Drug utilization, Drug monitoring

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Expecting the unexpected-drug safety, pharmacovigilance, and the prepared mind

Article Abstract:

The clinician's careful observation characterizes the full safety profile of the effects of a new drug in 'real world' practice that is far removed from clinical-trial conditions. The capacity to recognize and investigate unexpected clinical events enables discovery in an observational science such as pharmacovigilance and the detection of such unanticipated effects depends on 'the prepared mind'.

Evaluation, Clinical trials, Clinical pharmacology

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