Independent clonal origin of multiple uterine leiomyomas that was determined by X chromosome inactivation and microsatellite analysis

Article Abstract:

The allelic status with 15 microsatellite markers was analyzed along with the X chromosome inactivation analysis to clarify the clonality and genetic relationships that are involved in the tumorigenesis of uterine leiomyomas. Results revealed that uterine leiomyomas are derived from a single cell but are generated independently in the uterus.

Genetic aspects, Cancer, Cancer genetics, Leiomyoma, X chromosome

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Incidence, severity, and determinants of perineal pain after vaginal delivery: A prospective cohort study

Article Abstract:

Frequency of perineal pain in the 6 weeks after vaginal delivery was determined and the association between perineal trauma and perineal pain was assessed. Results indicate that perineal pain was very severe and frequent for women with increased perineal trauma.

Complications and side effects, Postnatal care, Natural childbirth

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