Cross-presentation of caspase-cleaved apoptic self antigens in HIV infection

Article Abstract:

The self-reactive effector [CD8.sup.+] T has contributed to the systemic immune activation during chronic HIV infection. The caspase-dependent cleavage of protein associated with apoptic cells have played a major role in the induction of self-reactive [CD*.sup.+] T cells responses, as the caspase-cleaved fragments are targeted to the processing machinery and are cross-presented by dendritic cells.

HIV infection, HIV infections, Dendrites, Apoptosis

---

Building the bionic T cell

Article Abstract:

Tumor immunologists have described a new strategy that has produced striking antitumor effects in mouse models by using T cells. Results highlight that the increase in costimulation can boost tumor immunotherapy providing new strategies to accomplish this boost in of adoptive T cell therapy.

Analysis, Cancer, Tumor antigens, Immunotherapy, Tumour antigens

---

Similar abstracts:

• Abstracts: CD8+ lymphocyte responses to antiretroviral therapy of HIV infection. Buffalo hump seen in HIV-associated lipodystrophy is associated with hyperinsulinemia but not dyslipidemia
• Abstracts: The prevention of Clostridium difficile associated diarrhoea in hospital
• Abstracts: Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. TP53 mutations and survival in squamous-cell carcinoma of the head and neck
• Abstracts: Care of the bereaved when postmortems are required. Always challenging, always changing
• Abstracts: The treatment of patients with TB and the role of the nurse

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.