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Decoding calcium signals involved in cardiac growth and function

Article Abstract:

This article discusses the importance of understanding calcium signaling in developing a treatment for human heart disease. The authors maintain calcium is pivotal in the regulation of cardiac contractility, growth and gene expression.

Author: Olson, Eric N., McKinsey, Timothy A., Frey, Norbert
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Health aspects, Calcium, Calcium (Chemical element)

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A decade of discovery in cardiac biology

Article Abstract:

The discoveries made in cardiac biology over past decade and the impact of future therapies for congenital and acquired heart diseases are focused. Further optimization of technologies for gene delivery and stem cell therapy promises to provide alternative means of repairing injured hearts.

Author: Olson, Eric N.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
HEALTH SERVICES, Ambulatory Health Care Services, Therapeutic Procedures, Usage, Therapeutics, Stem cell transplantation

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Deacetylase inhibition promotes the generation and function of regulatory T cells

Article Abstract:

The role of the histone/protein deacetylases (HDACs) inhibitors in promoting the generation and the function of regulatory T cells is discussed. These inhibitors are found to improve the numbers, as well as the suppressive functions of such cells.

Author: Olson, Eric N., Turka, Laurence A., Bin Li, Hancock, Wayne W., Greene, Mark I., Tao, Ran, de Zoeten, Edwin F., Ozkaynak, Engin, Chunxia Chen, Liqing Wang, Porrett, Paige M., Wells, Andrew D.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Histones, Genetic transcription, Transcription (Genetics), T cells, Chemical properties

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Subjects list: Care and treatment, Research, United States, Heart diseases, Gene expression
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