Deletion of cytosolic phospholipase A2 promotes striated muscle growth

Article Abstract:

The fundamental role played by cytosolic phospholipase A2 (PLA2) in regulation of cellular homeostasis, inflammation and tumorigenises is illustrated. Negative regulation of normal growth of striated muscle, stress-induced hypertrophic growth of the heart and IGF-1 signaling are the three new functions of cytosolic PLA2.

Health aspects, Growth, Inflammation, Muscles, Phospholipases, Cytosol, Tumor antigens, Homeostasis, Company growth, Tumour antigens

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Genetic clues to the pathogenesis of Parkinson's disease

Article Abstract:

There is an explosion in the rate of discovery of genetic defects linked to Parkinson's disease. Although these breakthroughs have not provided a direct explanation for the disease process, they have helped transform Parkinson's disease research by providing tangible clues to the neurobiology of the disorder.

Genetic aspects, Parkinson's disease, Parkinson disease

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Advantage of rare HLA supertype in HIV disease progression

Article Abstract:

The effect of Human Leukocyte Antigen(HLA) to determine the specificity and repertory of immune responses in progression with HIV disease is illustrated. Statistical analysis is carried out to test the strength of HLA association with nonparamatic Wilcoxon rank.

Development and progression, HIV (Viruses), HIV, HLA histocompatibility antigens, HLA antigens, Histocompatibility antigens

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