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Early vs. late administration of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention of acute ST-segment elevation myocardial infarction

Article Abstract:

Primary percutaneous coronary intervention (PCI) has always been the reperfusion strategy in ST-segment elevation myocardial infarction (STEMI) and meta-analysis of trials of early vs. late intravenous administration of Gp IIb/IIIa inhibitors in STEMI was done. In 6 meta-analysis early administration of inhibitors in STEMI helped improve coronary patency with positive trends for clinical outcomes, but further evaluations are suggested.

Author: Thomas, David, Montalescot, Gilles, Borentain, Maria, Payot, Laurent, Collet, Jean Philippe
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
Glycoproteins

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Distal microcirculatory protection during percutaneous coronary intervention in acute ST-segment elevation myocardial infarction

Article Abstract:

The study conducted determines whether protection of the distal microcirculation from throm-boembolic debris liberated during primary percutaneous coronary intervention (PCI) results in improved reperfusion and decreased infract size. The result reveals that a distal balloon occlusion and aspiration system effectively retrieves embolic debris in most patients with acute segment elevation myocardial infarction undergoing emergent PCI.

Author: Lansky, Alexandra J., Cox, David A., Stone, Gregg W., Turco, Mark, Brodie, Bruce R., Rutherford, BArry D., Gibbons, Raymond J, Mehran, Roxana, Webb, John, Dulas, Daniel, Schultheisis, Heinz P., Kalynch, Anna, Qureshi, Mansoor, Krocoff, Mitchell W., Antoniuci, David
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Risk factors, Microcirculation disorders

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Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction

Article Abstract:

A study was conducted to assess the value of stem cell mobilization by Granulocyte Colony Stimulating Factor (G-CSF) therapy in patients with acute Myocardial Infarction (MI). The results showed that stem cell mobilization by G-CSF therapy in patients with acute MI and successful mechanical reperfusion has no influence on infarct size, left ventricular function, or coronary restenosis.

Author: Kastrati, Adnan, Dirschinger, Josef, Mehilli, Julinda, Schwaiger, Markus, Bollwein, Hildegard, Schmitt, Claus, Seyfarth, Melchior, Zohlnohofer, Dietlind, Ott, Ilka, Schomig, Kathrin, Michalk, Fabian, Ibrahim, Tareq, Meisetschlager, Gunther, Wedel, Jasper von, Schornig, Albert
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Granulocytes, Granulocyte colony-stimulating factor, Cellular therapy, Cell therapy

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Subjects list: Care and treatment, Research, United States, Heart attack
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