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Effect of Prolonged Methylprednisolone Therapy in Unresolving Acute Respiratory Distress Syndrome

Article Abstract:

Prolonged treatment with methylprednisolone may be beneficial in patients with acute respiratory distress syndrome (ARDS). Mortality rates in ARDS patients often exceed 50%. Researchers assigned 16 ARDS patients to receive methylprednisolone treatment for 32 days and 8 ARDS patients to receive a placebo. Methylprednisolone improved lung function and reduced the risk of multiple organ failure. Mortality rates during hospitalization were 62% in the placebo group and 12% in the methylprednisolone group.

Author: Meduri, G. Umberto MD, Headley, A. Stacey MD, Golden, Emmel MD, Carson, Stephanie J., Umberger, Reba A. RN, Kelso, Tiffany PharmD, Tolley, Elizabeth
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

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Effect of Prolonged Methylprednisolone Therapy in Unresolving Acute Respiratory Distress Syndrome

Article Abstract:

Prolonged treatment with methylprednisolone may be beneficial in patients with acute respiratory distress syndrome (ARDS). Mortality rates in ARDS patients often exceed 50%. Researchers assigned 16 ARDS patients to receive methylprednisolone treatment for 32 days and 8 ARDS patients to receive a placebo. Methylprednisolone improved lung function and reduced the risk of multiple organ failure. Mortality rates during hospitalization were 62% in the placebo group and 12% in the methylprednisolone group.

Author: Tolley, Elizabeth A., Meduri, G. Umberto MD, Headley, A. Stacey MD, Golden, Emmel MD, Carson, Stephanie J., Umberger, Reba A. RN, Kelso, Tiffany PharmD
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

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Effect of Prolonged Methylprednisolone Therapy in Unresolving Acute Respiratory Distress Syndrome

Article Abstract:

Prolonged treatment with methylprednisolone may be beneficial in patients with acute respiratory distress syndrome (ARDS). Mortality rates in ARDS patients often exceed 50%. Researchers assigned 16 ARDS patients to receive methylprednisolone treatment for 32 days and 8 ARDS patients to receive a placebo. Methylprednisolone improved lung function and reduced the risk of multiple organ failure. Mortality rates during hospitalization were 62% in the placebo group and 12% in the methylprednisolone group.

Author: Meduri, G. Umberto MD, Headley, A. Stacey MD, Golden, Emmel MD, Carson, Stephanie J., Umberger, Reba A. RN, Kelso, Tiffany PharmD, Tolley, Elizabeth
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998

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Comment about this article or add new information about this topic:

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Subjects list: Evaluation, Drug therapy, Acute respiratory distress syndrome, Adult respiratory distress syndrome, Methylprednisolone
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