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Effect of lung-volume-reduction surgery in patients with severe emphysema

Article Abstract:

Lung-volume reduction surgery may improve the health of people with severe emphysema. During this type of surgery, surgeons remove portions of the diseased lung. Researchers randomly assigned 48 patients with severe emphysema to receive lung-volume-reduction surgery or drug therapy consisting of corticosteroids, beta-agonists, and theophylline. Twenty-one percent of the surgery patients died compared to 12% of the drug therapy group. Six months later, the surgery group had better lung function whereas the drug therapy group had worse lung function. Walking distance increased in the surgery patients but decreased in the drug therapy patients.

Author: Geddes, Duncan, Davies, Michael, Koyama, Hiroshi, Hansell, David, Pastorino, Ugo, Pepper, John E., Agent, Penny, Cullinan, Paul, MacNeill, Stephanie J., Goldstraw, Peter
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000

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Patients at high risk of death after lung-volume-reduction surgery

Article Abstract:

Patients with severe emphysema will not benefit from lung-volume reduction surgery, according to a study of 1,033 patients. During this type of surgery, the damaged parts of the lung are removed. Patients with severe emphysema who received the surgery had higher death rates than those who were treated with medication.

Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Lungs, Lung surgery

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Subjects list: Surgery, Emphysema, Pulmonary, Emphysema
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