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Effect of nebulized ipratropium on the hospitalization rates of children with asthma

Article Abstract:

Children with a severe exacerbation of asthma may benefit from a dose of ipratropium. Researchers randomly assigned 434 children who were seen at a hospital emergency department to receive ipratropium or a placebo in addition to several doses of albuterol. Among children with moderate asthma, hospitalization rates were similar in both groups. Among children with severe asthma, only 37% of children receiving ipratropium were hospitalized, compared to 53% of those receiving a placebo.

Author: Zaritsky, Arno, Pestian, John, Qureshi, Faiqa, Davis, Paris
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
Children, Hospitalization, Ipratropium

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Long-term effects of budesonide or nedocromil in children with asthma

Article Abstract:

Inhaled budesonide appears to improve airway function in children with asthma, according to a study of 1,041 children who used inhaled budesonide, inhaled cedocromil, or an inhaled placebo. Nedocromil was no better than the placebo in treating asthma. Neither drug improved lung function significantly.

Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Budesonide, Nedocromil

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Subjects list: Evaluation, Drug therapy, Asthma in children, Childhood asthma
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