Nitric oxide modulates angiotensin II-induced drinking behavior in the near-term ovine fetus

Article Abstract:

Nitric oxide is responsible for drinking and swallowing in response to angiotensin II in the brain, according to a study in pregnant sheep. The fetal lambs increased swallowing after angiotensin II injections into the brain, a response that was blocked by chemicals that block nitric oxide.

Nitric oxide, Drinking (Physiology), Angiotensin, Angiotensins

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Effects of central angiotensin II receptor antagonism on fetal swallowing and cardiovascular activity

Article Abstract:

Pregnant women should be cautious when using ACE inhibitors or angiotensin II receptor blockers. A study in sheep shows that these drugs can inhibit fetal swallowing. This could be dangerous because the fetus regulates the amount of amniotic fluid by swallowing it.

Complications and side effects, ACE inhibitors, Angiotensin converting enzyme inhibitors, Angiotensin II receptor blockers

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Anticholinergic suppression of ovine fetal swallowing activity

Article Abstract:

Brain wave patterns in near-term sheep fetuses be may altered, and associated fetal swallowing activity decreased, by the administration of atropine sulfate. Three specific brain wave patterns reflecting distinct behavioral states and activities in the fetuses of six ewes were observed when no drug was administered. The most swallowing activity occurred during low-voltage patterns. Atropine sulfate decreased the occurrence of low-voltage brain activity and total swallowing rates. The association between brain wave activity and swallowing rates was unaffected.

Atropine

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