Effects of pregnancy on femoral microvascular responses in the rat

Article Abstract:

Micro blood vessels in pregnant rats do not seem to respond differently than non-pregnant rats when exposed to chemicals that induce contraction and relaxation. Small blood vessels from pregnant and non-pregnant rats' legs were exposed to contraction-inducing chemicals including potassium chloride, angiotensin II, and phenylephrine and a relaxation-inducing chemical called acetylcholine. A combination of nitroarginine with phenylephrine, potassium chloride, or acetylcholine was analyzed also. The effects in pregnant and non-pregnant rats were similar. Nitric oxide did not seem to play a major role in vessel relaxation.

Mice as laboratory animals, House mouse, Blood vessels, Vasodilation

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Urocortin in pregnancy

Article Abstract:

Urocortin does not appear to be involved in the increase in free corticotropin-releasing hormone in the later stages of pregnancy. Urocortin is a protein similar to corticotropin-releasing hormone. Corticotropin-releasing hormone is normally bound to protein, but in the later stages of pregnancy, it is released in the free form. An analysis of tissue samples of placenta and fetal membranes revealed no evidence of urocortin even though corticotropin-releasing hormone was present.

Corticotropin releasing hormone, Corticotropin-releasing hormone

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Lipoprotein metabolism during normal pregnancy

Article Abstract:

Blood levels of low-density lipoprotein (LDL) cholesterol appear to increase during pregnancy. This form of cholesterol has been linked to an increased risk of coronary artery disease. The magnitude of the increase may identify women at increased risk of heart disease later in life.

Cholesterol, LDL, VLDL cholesterol lipoproteins, Lipoproteins

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