Deficiency of the Humoral immune Response to Measles Vaccine in Infants Immunized at Age 6 Months

Article Abstract:

Infants younger than one year may not benefit from measles vaccination because their immune system is not mature enough. Normally, children are vaccinated against measles at age 12 to 15 months but those under 12 months have the highest risk of severe illness from measles. In a study of 27 6-month-old infants, 26 9-month-old infants and 34 12-month-old infants who received the measles vaccine, only 36% of the 6-month-old infants achieved protective blood levels of antibodies against measles, compared to 100% of the other infants.

Measles vaccine, Measles vaccines

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Postlicensure effectiveness of varicella vaccine during an outbreak in a child care center

Article Abstract:

The varicella virus vaccine was highly effective in preventing chickenpox during an outbreak at a Georgia day-care center in 1996. In a retrospective study of 148 children, 55% developed varicella during the 15-week outbreak. The disease struck 88% of the 82 unvaccinated children and only 14% of the 66 who took the vaccin. Vaccinated children suffered milder illnesses. The vaccine was less effective in those with asthma. The varicella vaccine was effective in all cases at preventing moderate-to-severe chickenpox.

Health aspects, Prevention, Day care centers, Chickenpox vaccine, Chickenpox vaccines, Chickenpox

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