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Etanercept plus standard therapy for Wegener's granulomatosis

Article Abstract:

Majority of patients with Wegener's granulomatosis have disease flares after conventional medications are tapered and there are no consistently safe, effective treatment for the maintenance of remission. A randomized, placebo-controlled trial is conducted to evaluate etanercept for the maintenance of remission in patients with Wegener's granulomatosis.

Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Risk factors, Wegener's granulomatosis, Etanercept

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Modafinil for excessive sleepiness associated with shift-work sleep disorder

Article Abstract:

The use of modafinil for treating sleepiness in patients with shift-work sleep disorder is evaluated. The results revealed that treatment with 200 mg of modafinil reduced the extreme sleepiness observed in patients with shift-work sleep disorder and resulted in small but significant improvement in performance as compared with placebo.

Author: Dinges, David F., Roth, Thomas, Walsh, James K., Czeisler, Charles A., Niebler, Gwendolyn E., Schwartz, Jonathan R.L., Hughes, Rod J., Arora, Sanjay, Wright, Kenneth P., Kingsbury, Lilliam
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Drug therapy, Sleep disorders, Modafinil

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Subjects list: United Kingdom, Dosage and administration
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