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Family studies in patients with the sleep apnea-hypopnea syndrome

Article Abstract:

Inherited facial structure may play a role in a familial tendency to the sleep apnea-hypopnea syndrome. The sleep apnea-hypopnea syndrome is characterized by loud snoring, episodes of breathing cessation or choking during sleep, and excessive daytime sleepiness. Researchers studied 51 first-degree relatives of patients with the syndrome and 51 randomly selected persons of similar age and physical characteristics (controls). Obese persons were excluded from the study, since obesity can contribute to sleep apnea. Relatives and controls completed questionnaires and participated in an overnight sleep assessment study. More relatives than controls reported snoring, choking and daytime sleepiness. Sleep study results showed that relatives had more episodes of breathing cessation, more frequent arousals and sleep disturbances and less slow-wave sleep than controls. Anatomic measurements indicated that relatives had narrower throats, jaw bones displaced toward the back of the skull, and longer soft palates.

Author: Mathur, Rajat, Douglas, Neil J.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1995
Risk factors

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A predictive morphometric model for the obstructive sleep apnea syndrome

Article Abstract:

The use of a formula incorporating several body measurements appears to be a useful way to identify patients with obstructive sleep apnea syndrome (OSAS). The body measurements include distance around the neck, body mass index, and inner mouth measurements. These measurements were made on 300 patients with suspected OSAS followed by a comprehensive sleep analysis. Nearly all of the patients fitting the formula model were later confirmed as having OSAS.

Author: Guilleminault, Christian, Efron, Bradley, Kushida, Clete A.
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1997
Diagnosis, Measurement, Body size, Body weights and measures, Mouth, Stomatognathic system, Neck

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Subjects list: Sleep apnea syndromes, Sleep apnea
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