Fetal interleukin-1 receptor antagonist gene polymorphism, intra-amniotic interleukin-1beta levels, and history of spontaneous abortion

Article Abstract:

A research was done to determine whether fetal carriage of specific alleles of the polymorphic interleukin-1 receptor antagonist gene was associated with previous pregnancy outcomes. Results indicate that these conditions are associated with reduced intra-amniotic interleukin-1 beta concentrations and an increased occurrence of spontaneous abortions in women with these conditions.

Pregnancy, Complications of, Pregnancy complications, Interleukin-1

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Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes

Article Abstract:

The relationship between preterm premature rupture of membranes, tumor necrosis factor-alpha was studied. The results revealed tumor necrosis factor-alpha allele 2 and/or heat shock protein-70 allele 2 carriage by the first-born fetus to be associated with preterm premature rupture of membranes in multifetal pregnancies.

Causes of, Heat shock proteins, Premature rupture of membranes, Premature rupture of the membrane, Tumor necrosis factor, Tumour necrosis factor

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Interleukin-4 and -10 gene polymorphisms and spontaneous preterm birth in multifetal gestations

Article Abstract:

The relationship between maternal and fetal carriage of different alleles of interleukin (IL)-4 and -10 gene polymorphism and pregnancy outcome in multiple gestations is determined. The maternal and fetal carriage of IL-4 allele is associated with an increased risk of spontaneous preterm birth in multifetal gestations.

Patient outcomes, Pregnancy, Interleukin-4, Interleukin-10

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