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Fundamental genetic findings net Nobels

Article Abstract:

The 2006 Nobel prizes in chemistry and in physiology or medicine recognized three scientists who revealed fundamental information about the roles and mechanisms of RNA in eukaryotic cells. Molecular biologists Andrew Z. Fire and Craig C. Mello were awarded the prize in physiology or medicine for their discovery of RNA interface, while the Nobel prize for chemistry was awarded to Roger Kornberg, for his work on the transfer of information from DNA to messenger RNA.

Author: Kuehn, Bridget M.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Achievements and awards, Nobel laureates, Molecular biologists, Nobel Prizes, RNA interference, Kornberg, Roger D., Fire, Andrew, Mello, Craig

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Genetic flaws found in aging stem cell lines

Article Abstract:

New research has provided evidence that human embryonic stem cells grown in culture accumulate changes in their genetic material over time, limiting the usefulness of aging stem cell lines. Using new and highly sensitive array technology, an international team of researchers has identified alterations in chromosomes and certain genes occurring over time in federally approved stem cell lines.

Author: Kuehn, Bridget M.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Stem cells, Human embryo

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Genetic information: How much can patients handle?

Article Abstract:

Proponents tout genome wide scans for disease causing genes as the future of medicine. The capability of the patients and their physicians to handle the vast and potentially ambiguous data that are provided to them, are discussed.

Author: Kuehn, Bridget M.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Physician and patient, Physician-patient relations, Genetic disorders, Informed consent (Medical law), Informed consent, Health risk communication

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Subjects list: Research, United States
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