Gene therapy showing promise in fighting melanoma

Article Abstract:

A new cancer vaccine has shown efficacy in treating a vicious form of melanoma in dogs. A research team from the University of Wisconsin-Madison School of Veterinary Medicine has developed a gene therapy approach wherein cancer cells can be recognized and killed by the animal's immune system. Prof Gregory MacEwen and research scientist Gary Hogge said the vaccine was used in treating 16 dogs with advanced stages of melanoma and was found to extend the life span of some animals and to shrink the tumor in some 20% of the treated animals.

Gene therapy, Cancer, University of Wisconsin

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New oral rotavirus vaccine helps prevent severe childhood diarrhea and vomiting

Article Abstract:

The first oral rotavirus vaccine touted to prevent the most serious effects of rotaviruses in infants has been granted FDA approval. The vaccine has been licensed for use in immunizing infants in a three-dose regimen at ages six months and two and four years. Acting FDA commissioner Michael A. Friedman said that symptoms of infection are milder and appear for a shorter duration once a child has received the vaccine. Severe diarrhea and vomiting in infants in the US are most commonly caused by rotavirus infections.

Prevention, Practice, Licensing agreements, United States. Food and Drug Administration, Rotavirus infections, Viral vaccines

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Vaccine shows promise for treating melanoma in mice

Article Abstract:

A new DNA-based vaccine that can trigger immunity where other vaccine types have failed shows potential for treating melanoma in mice. Scientists at New York's Memorial Sloan-Kettering Cancer Center led by Dr Alan Houghton used a 'needleless syringe' called a gene gun to induce an immune attack in mice, immunizing the mice with either a purified form of mouse DNA or the human DNA. Researchers found that in mice injected with human DNA, tumors had regressed by 86% and a marked immune response was detected.

Usage, DNA, Vaccines

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