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Genetic susceptibility to type 2 diabetes and implications for antidiabetic therapy

Article Abstract:

The article discusses various genetic loci and mechanisms that are found to be associated with the onset of type 2 diabetes in humans. The various antidiabetic and pharmacologic therapies are found to be quite effective in the treatment of the disease.

Author: Florez, Jose C., Moore, Allan F.
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2008
Genetic aspects, Type 2 diabetes, Pharmacogenetics, Pharmacogenomics, Single nucleotide polymorphisms

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Molecular neurobiology of drug addiction

Article Abstract:

The abnormal usage of drugs results in addiction, and it can be viewed as a form of drug-induced neural plasticity. Many drugs cause both tolerance and sensitization, and some have side effects, which are decreasing over time while others increase.

Author: Nestler, Eric J., Chao, Jennifer
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2004
Drug abuse, Cell nuclei, Cell nucleus, Molecular neurobiology

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Toward Alzheimer therapies based on genetic knowledge

Article Abstract:

The genetic analysis is used for the early detection and diagnostic of the Alzheimer's disease. The need for the revaluation of this genetic analysis for treating complex diseases is discussed.

Author: Hardy, John
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2004
Alzheimer's disease, Cholesterol, DNA sequencers, Immunotherapy

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Subjects list: Care and treatment, Research
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