HIV-1 RNA levels and development of clinical disease in two different adolescent populations

Article Abstract:

The level of HIV in the blood determines the progression of the disease in HIV-infected teenagers, according to a study of hemophiliacs who were infected by contaminated blood transfusions and teenagers who were sexually infected. This contradicts the belief that teenagers tolerate the infection better than older patients.

HIV infection in children, Pediatric HIV infections

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HIV-1 RNA levels in an African population-based cohort and their relation to CD4 lymphocyte counts and World Health Organization clinical staging

Article Abstract:

Higher viral levels in the blood of HIV patients in Africa was linked to more severe illness, but only in patients who had been infected for 6 years or less. Researchers used the nucleic acid sequence-based amplification procedure (NASBA) test kit to measure HIV RNA in blood from 105 HIV patients.

HIV infection, HIV infections

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Predictive markers of HIV-related weight loss and determination of differences between populations with weight loss stratified by opportunistic processes

Article Abstract:

High viral levels as measured by HIV RNA are a risk factor for weight loss in HIV patients but only when they occur at week 8 of the infection. This means that patients can reduce their risk of weight loss by lowering blood levels of the virus.

Risk factors, HIV patients, Weight loss

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