HIV-1 pathogenesis

Article Abstract:

ANNOTATION: "HIV SPECIAL" The interaction of the viruses at different levels in the cells is illustrated. The pathogenic infection about HIV is debated and stated that measures to eradicate it remains subtle. Viral pathogenecity is a result of direct effect of replication on infected cells and indirect effects on uninfected cells.

Science & research, HIV infection, HIV infections, AIDS research

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HIV nuclear import: what's the flap?

Article Abstract:

Research is presented on the 'DNA flap', which is a triple stranded HIV cDNA intermediate of reverse transcription, and may be a component of HIV nuclear import. Issues discussed include nuclear translocation of viral nucleic acids, the improvement of anti-retroviral drug design, and gene therapy.

Physiological aspects, DNA, Gene therapy, Translocation (Genetics), Pharmaceutical research

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A new latent HIV reservoir

Article Abstract:

This article examines research on HIV genetics and viral latency in human T cells. Topics addressed include the progression of HIV infection, thymocytes, gene expression and transcription.

Infection, T cells, Antiviral agents

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