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HTLV-II-associated cutaneous T-cell lymphoma in a patient with HIV-1 infection

Article Abstract:

Researchers describe the case of a 38-year-old intravenous drug addict who was HIV-infected and developed a skin disease. Skin biopsies tested positive for HTLV-II, a virus distantly related to HIV. His skin had been infiltrated by T cells and he was diagnosed with cutaneous T-cell lymphoma. Many of the T cells were CD8+ cells. In healthy people, HTLV-II may not be dangerous, but people with weak immune systems may develop serious disease. The patient described in this case died one year later.

Author: Poiesz, Bernard, Dube, Dipak, Dube, Syamalima, Love, Jayne, Papsidero, Lawrence, Uner, Aysegul, Hutchinson, Robert
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Health aspects, Diseases, HIV patients, HTLV-II infections

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Mechanisms of disease: persistence of the Epstein-Barr virus and the origins of associated lymphomas

Article Abstract:

The Epstein Barr virus (EBV) immortalizes human B lymphocytes in culture which leads to human diseases like the cancer and autoimmune disease. When the EBV infected cell cannot move out of the cell cycle, as it has become a resting memory B cell, and the cytotoxic T-cell does not function properly then it leads to lymphoma.

Author: Gross, Andrew, Thorley-Lawson, David A.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
England, Care and treatment, Risk factors, B cells, Epstein-Barr virus

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A seven-year-old girl with the superior vena cava syndrome after treatment for a peripheral rhabdomyosarcoma

Article Abstract:

A seven-year-old girl developed a type of cancer called lymphoma several years after she had received chemotherapy for a tumor called rhabdomyosarcoma.

Author: Larsen, Eric, De Leval, Laurence
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Case studies, Complications and side effects, Cancer in children, Childhood cancer, Chemotherapy

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Subjects list: Causes of, Lymphomas
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