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Hematologic effects of maternal antiretroviral therapy and transmission prophylaxis in HIV-1-exposed uninfected newborn infants

Article Abstract:

Hematologic alterations observed during the first 3 months of life in HIV-exposed uninfected infants subjected to antiretroviral medication before and after birth is investigated. The results have shown that antiretroviral transmission prophylaxis is associated with anemia and neutropenia in HIV-uninfected infants during the first 3 months of life and also that anemia is more profound in highly active antiretroviral therapy (HAART)-exposed infants.

Author: Schmitz, Thomas, Feiterna-Sperling, Cornelia, Weizsaecker, Katharina, Buhrer, Christoph, Casteleyn, Simone, Loui, Andrea, Wahn, Volker, Obladen, Michael
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007
Prevention, Causes of, Complications and side effects, Infants (Newborn), Newborn infants, HIV infection in children, Pediatric HIV infections, Blood diseases, Hematologic diseases, Prenatal drug exposure, Clinical report

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Trends in antiretroviral drug resistance and clade distribution among HIV-1-infected blood donors in Sao Paulo, Brazil

Article Abstract:

Rates of drug resistance mutations in antiretroviral-naive Sao Paulo blood donors are analyzed with recently acquired or established HIV-1 infections and characterized clade diversity in this population. The prevalence of drug-resistant mutations among new diagnosed persons in Sao Paulo city is found to be low and similar to what has been described in Europe and the United States.

Author: Busch, Michael P., Barreto, Claudio C., Nishyia, Anna, Araujo, Luciano V., Ferreira, Jodo E., Sabino, Ester C.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
Europe, Brazil, Blood donors, Blood donation

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Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment-naive and -experienced patients in Singapore

Article Abstract:

A study is done to determine the frequency of drug resistance mutations among antiretroviral treatment-naive and -experienced patients infected with CRF01_AE virus. The result was that the pattern of treatment-related mutations in CRF01_AE virus differed from that in subtype B virus at a number of positions determining drug resistance.

Author: Li-Yang Hsu, Subramaniam, Ravathi, Bacheler, Lee, Paton, Nicholas I.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
Singapore, Gene mutations, Gene mutation

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Subjects list: Health aspects, Research, Dosage and administration, Antiviral agents, Antiretroviral agents, United States, Drug resistance
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