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High-risk patients with ventricular preexcitation -- a pendulum in motion

Article Abstract:

Radiofrequency catheter ablation treatment may be effective for treating Wolff-Parkinson-White syndrome even if the patient has no symptoms, according to a study published in 2003. Other studies have shown that these patients have a low risk of sudden death from a severe arrhythmia. So many doctors decided not to treat them. This study shows that this decision may need to be reconsidered.

Author: Basson, Craig T., Lerman, Bruce B.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
Care and treatment, Evaluation, Catheter ablation

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A molecular basis for Wolff-Parkinson-White syndrome

Article Abstract:

A mutation in the gene for the gamma2 regulatory subunit of AMP-activated protein kinase has been linked to a heart arrhythmia called Wolff-Parkinson-White syndrome. The arrhythmia is caused by an abnormal electrical pathway between the upper and lower parts of the heart.

Author: Basson, Craig T.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Health aspects, Editorial, Gene mutations, Gene mutation, Genetic aspects

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Sparking the failing heart

Article Abstract:

More than half the number of patients suffering from congestive heart failure (CHF) die by ventricular tachycardia. Most patients do not survive beyond a year after receiving the diagnosis.

Author: Basson, Craig T., Farr, Maryjane A.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Mortality, Causes of, Risk factors, Congestive heart failure, Ventricular tachycardia

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Subjects list: Wolff-Parkinson-White syndrome
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