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Hormone Replacement Therapy and Risk of Breast Cancer With a Favorable Histology: Results of the Iowa Women's Health Study

Article Abstract:

Long-term use of hormone replacement therapy (HRT) appears to increase the risk of breast cancer but the type of cancer has a good prognosis. Among 37,105 women in the Iowa Women's Health Study, 1,520 developed breast cancer. Use of HRT increased the risk of cancer about two to four times the normal rate, but the cancer was a type of cancer with a good prognosis. HRT use did not increase the risk of cancer that has a traditionally poor prognosis.

Author: Morrow, Monica, Gapstur, Susan M., Sellers, Thomas A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999

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Combined hormone therapy and breast cancer: a single-edged sword

Article Abstract:

Postmenopausal women should only use hormone replacement therapy (HRT) that includes progesterone for menopausal symptoms only and should stop taking HRT once the symptoms stop. A large study called the Women's Health Initiative found that hormone replacement therapy can increase the risk of breast cancer. In addition, it can make breasts denser, which would make it harder for a mammogram to detect the cancer.

Author: Morrow, Monica, Gann, Peter H.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Editorial, Complications and side effects, Hormone replacement therapy

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Alcohol and Breast Cancer: Review of Epidemiologic and Experimental Evidence and Potential Mechanisms

Article Abstract:

A summary of the animal and human research on the link between alcohol consumption and breast cancer is presented. Although the mechanism is unclear, epidemiological studies have consistently reported an increased risk of breast cancer in women who drink alcohol on a regular basis.

Author: Gapstur, Susan M., Singletary, Keith W.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Drinking of alcoholic beverages, Drinking (Alcoholic beverages)

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Subjects list: Health aspects, Risk factors, Breast cancer, Hormone therapy
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