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Idiopathic arterial calcification of infancy

Article Abstract:

Idiopathic arterial calcification of infancy (IACI) is a congenital illness that generally kills infants born with it within the first six months of life. With IACI, arteries calcify and become inelastic. Symptoms are unexplained congestive heart failure and high blood pressure. X rays can show up the calcifications. Some infants treated with a medication that inhibits calcium crystal precipitation or with combinations of steroids, estrogen, and thyroid hormones have survived, and a few infants have made a spontaneous recovery. A case history is reported of a 1450 gram baby delivered at 30 weeks gestation when an ultrasound scan suggested possible heart disease. He developed severe respiratory distress and intermittent hypertension. A chest X ray at 25 days revealed a calcified abdominal aorta and heart. Heart failure caused death at one month of age. An autopsy found an enlarged heart and calcification throughout the major arteries and in the kidneys.

Author: Green, David W., Laughlin, William R.
Publisher: American Medical Association
Publication Name: Archives of Pediatrics & Adolescent Medicine
Subject: Health
ISSN: 1072-4710
Year: 1996
Diagnosis, Arteries, Calcification

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Acute pulmonary hemorrhage in infants associated with exposure to Stachybotrys atra and other fungi

Article Abstract:

Pulmonary hemorrhage in a group of Cleveland babies was linked to exposure to a fungus called Stachybotrys atra. This fungus can grow in areas of high humidity and homes with water damage. When 10 infants with bleeding in their lungs were treated at a Cleveland hospital, epidemiologists compared their home conditions with 30 healthy infants. Levels of fungus in air samples were much higher in the homes of the sick infants than the homes of the healthy infants. Many of the sick infants' homes were in a neighborhood of old homes, many of which had plumbing leaks and other signs of water damage.

Author: Dearborn, Dorr G., Etzel, Ruth A., Montana, Eduardo, Sorenson, W.G., Kullman, Greg J., Allan, Terrance M.
Publisher: American Medical Association
Publication Name: Archives of Pediatrics & Adolescent Medicine
Subject: Health
ISSN: 1072-4710
Year: 1998
Health aspects, Molds (Fungi)

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Pulmonary Hemorrhage in an Infant Following 2 Weeks of Fungal Exposure

Article Abstract:

Researchers report the case of a 40-week-old baby who developed bleeding in his lungs caused by exposure to mold and tobacco smoke. He visited his grandfather's home in St Louis, Mo, for 2-weeks and developed this condition after returning home. The grandfather's house had mold damage caused by a wet basement. On the train ride back home, the baby was exposed to tobacco smoke. Two fungi associated from the house are known to produce toxins: Penicillium and Trichoderma. Stachybotrys atra was not isolated from air or surface samples taken from the house.

Author: Novotny, William E., Dixit, Anupma
Publisher: American Medical Association
Publication Name: Archives of Pediatrics & Adolescent Medicine
Subject: Health
ISSN: 1072-4710
Year: 2000
Case studies

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Subjects list: Diseases, Infants, Causes of, Hemorrhage, Lung diseases, Fungal, Fungal lung diseases
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